Allium sativum (garlic) inhibits lipid synthesis by Candida albicans.
نویسندگان
چکیده
The effect of aqueous garlic extract on the macromolecular synthesis of Candida albicans was studied. Protein and nucleic acid syntheses were inhibited to the same extent as growth, but lipid synthesis was completely arrested. Blockage of lipid synthesis is likely an important component of the anticandidal activity of garlic.
منابع مشابه
Allyl alcohol and garlic (Allium sativum) extract produce oxidative stress in Candida albicans.
Both the growth and respiration of Candida albicans are sensitive to extracts of Allium sativum and investigations into the anticandidal activities are now focussing on the purified constituents to determine the targets of inhibition. Of particular interest is allyl alcohol (AA), a metabolic product that accumulates after trituration of garlic cloves. Putative targets for AA were investigated b...
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ورودعنوان ژورنال:
- Antimicrobial agents and chemotherapy
دوره 30 3 شماره
صفحات -
تاریخ انتشار 1986